Publications Fundamental Research

  • Agnandji ST, Fendel R, Mestré M, Janssens M, Vekemans J, Held J, Gnansounou F,et al.“ Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D). PLoS One. 2011 Apr 11;6(4):e18559. [Abstract] [Free Full Article]

  • Boldt AB, Messias-Reason IJ, Lell B, Issifou S, Pedroso ML, Kremsner PG, Kun JF. Haplotype specific-sequencing reveals MBL2 association with asymptomatic Plasmodium falciparum infection. Malar J. 2009 May 11;8:97. [Abstract] [Free Full Article]

  • Dietmann A, Helbok R, Lackner P, Fischer M, Reindl M, Lell B, Issifou S, Kremsner PG, Schmutzhard E. Endoglin in African children with Plasmodium falciparum malaria: a novel player in severe malaria pathogenesis? J Infect Dis. 2009 Dec 15;200(12):1842-8. [Abstract]

  • Enderes C, Kombila D, Dal-Bianco M, Dzikowski R, Kremsner P, Frank M. Var Gene promoter activation in clonal Plasmodium falciparum isolates follows a hierarchy and suggests a conserved switching program that is independent of genetic background. J Infect Dis. 2011 Nov 15;204(10):1620-31. [Abstract]

  • Esen M, Mordmüller B, de Salazar PM, Adegnika AA, Agnandji ST, Schaumburg F, Hounkpatin AB, Brückner S, Theisen M, Bélard S, Ngoa UA, Issifou S, Yazdanbakhsh M, Kremsner PG. Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura. Vaccine. 2012 Dec 14;30(52):7621-4. [Abstract]

  • Faik I, Oyedeji SI, Idris Z, de Messias-Reason IJ, Lell B, Kremsner PG, Kun JF. Ficolin-2 levels and genetic polymorphisms of FCN2 in malaria. Hum Immunol. 2011 Jan;72(1):74-9. [Abstract]

  • Frank M, Lehners N, Mayengue PI, Gabor J, Dal-Bianco M, Kombila DU, Ngoma GM, Supan C, Lell B, Ntoumi F, Grobusch MP, Dietz K, Kremsner PG. A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon. Malar J. 2011 Oct 17;10:304. [Abstract] [Free Full Article]

  • Hanel SA, Velavan TP, Kremsner PG, Kun JF. Novel and functional regulatory SNPs in the promoter region of FOXP3 gene in a Gabonese population. Immunogenetics. 2011 Jul;63(7):409-15. [Abstract]

  • Idris ZM, Yazdanbakhsh M, Adegnika AA, Lell B, Issifou S, Noordin R. A pilot study on cytotoxic T lymphocyte-4 gene polymorphisms in urinary schistosomiasis. Genet Test Mol Biomarkers. 2012 Jun;16(6):488-92. [Abstract] [Free Full Article]

  • Jepsen MP, Jogdand PS, Singh SK, Esen M, Christiansen M, Issifou S, Hounkpatin AB, Ateba-Ngoa U, Kremsner PG, Dziegiel MH, Olesen-Larsen S, Jepsen S, Mordmüller B, Theisen M. The malaria vaccine candidate GMZ2 elicits functional antibodies in individuals from malaria endemic and non-endemic areas. J Infect Dis. 2013 Aug 1;208(3):479-88. [Abstract]

  • Labuda LA, Ateba-Ngoa U, Feugap EN, Heeringa JJ, van der Vlugt LE, Pires RB, Mewono L, Kremsner PG, van Zelm MC, Adegnika AA, Yazdanbakhsh M, Smits HH. Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis. PLoS Negl Trop Dis. 2013;7(3):e2094. [Abstract] [Free Full Article]

  • Meurs L, Labuda L, Amoah AS, Mbow M, Ngoa UA, Boakye DA, Mboup S, Dièye TN, Mountford AP, Turner JD, Kremsner PG, Polman K, Yazdanbakhsh M, Adegnika AA. Enhanced pro-inflammatory cytokine responses following Toll-like-receptor ligation in Schistosoma haematobium-infected schoolchildren from rural Gabon. PLoS One. 2011;6(9):e24393. [Abstract] [Free Full Article]

  • Mombo-Ngoma G, Oyakhirome S, Ord R, Gabor JJ, Greutélaers KC, Profanter K, Greutélaers B, Kurth F, Lell B, Kun JF, Issifou S, Roper C, Kremsner PG, Grobusch MP. High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children. 2011 May 14;10:123. [Abstract] [Free Full Article]

  • Nemeth J, Winkler HM, Boeck L, Adegnika AA, Clement E, Mve TM, Kremsner PG, Winkler S. Specific cytokine patterns of pulmonary tuberculosis in Central Africa. Clin Immunol. 2011 Jan;138(1):50-9. [Abstract]

  • Selman MH, de Jong SE, Soonawala D, Kroon FP, Adegnika AA, Deelder AM, Hokke CH, Yazdanbakhsh M, Wuhrer M. Changes in antigen-specific IgG1 Fc N-glycosylation upon influenza and tetanus vaccination. Mol Cell Proteomics. 2012 Apr;11(4):M111.014563. [Abstract] [Free Full Article]

  • Seydel LS, Petelski A, van Dam GJ, van der Kleij D, Kruize-Hoeksma YC, Luty AJ, Yazdanbakhsh M, Kremsner PG. Association of in utero sensitization to Schistosoma haematobium with enhanced cord blood IgE and increased frequencies of CD5- B cells in African newborns. Am J Trop Med Hyg. 2012 Apr;86(4):613-9. [Abstract] [Free Full Article]

  • van der Vlugt LE, Labuda LA, Ozir-Fazalalikhan A, Lievers E, Gloudemans AK, Liu KY, Barr TA, Sparwasser T, Boon L, Ngoa UA, Feugap EN, Adegnika AA, Kremsner PG, Gray D, Yazdanbakhsh M, Smits HH. Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells. PLoS One. 2012;7(2):e30883. [Abstract] [Free Full Article]

  • Velavan TP, Büyükyazici B, Kremsner PG, Kun JF. Combined promoter haplotypes of the IL10R genes are associated with protection against severe malaria in Gabonese children. Immunogenetics. 2012 Feb;64(2):87-95. [Abstract]

  • Velavan TP, Bechlars S, Huang X, Kremsner PG, Kun JF. Novel regulatory SNPs in the promoter region of the TNFRSF18 gene in a Gabonese population. Braz J Med Biol Res. 2011 May;44(5):418-20. [Abstract]